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  • Gavin McGowen
February 13, 2020

BH3 MIMETICS

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces […]
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February 16, 2020

ALLERGIES & CYTOKINES

The release of cytokines is central to almost every stage of the immune response to allergens… how do you turn down the cytokines and stop the body […]
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February 17, 2020

ANTI-APOPTOTIC PATHWAYS

Evading apoptosis in cancer Carcinogenesis is a mechanistically complex and variable process with a plethora of underlying genetic causes. Cancer development consists of a multitude of […]
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February 17, 2020

EPIGENETIC MODIFIERS

Epigenetic Modifiers Exacerbate Oxidative Stress In Renal Proximal Tubule Cells Epigenetic Modifiers As Anticancer Drugs: Effectiveness Of Valproic Acid In Neural Crest-Derived Tumor Cells Epigenetic Modifiers […]
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February 17, 2020

BIM aka BCL2L11

A Bim-Targeting Strategy Overcomes Adaptive Bortezomib Resistance In Myeloma Through A Novel Link Between Autophagy And Apoptosis A Bioinformatic And Mechanistic Study Elicits The Antifibrotic Effect […]
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February 19, 2020

NEUROINFLAMMATION

… -(5-methylpyridin-2-yl)− 1H-pyrazol-5-yl) pyrazolo [1, 5-a] pyrimidine-3-carboxamide as a new potential PET agent for imaging of IRAK4 enzyme in neuroinflammation … -1 gp120 and Methamphetamine-mediated Induction […]
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April 6, 2020

ANTI-VIRAL EFFECTS OF FLAVONOIDS & POLYPHENOLS

-drug interaction potential of 1, 5-dicaffeylquinic acid, a new herbal drug for the treatment of hepatitis B and human immunodeficiency virus … -enriched extract from Myrothamnus […]
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July 6, 2020

ANTI ADIPOGENIC

Molecular regulation of adipogenesis and potential anti -adipogenic bioactive molecules anti ‐adipogenic regulation underlies hepatic stellate cell transdifferentiation Adipogenic and anti -adipogenic factors in the pituitary […]
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July 6, 2020

ADIPOGENESIS

Molecular regulation of adipogenesis Transcriptional regulation of adipogenesis Regulating adipogenesis New developments in adipogenesis Inhibition of adipogenesis by Wnt signaling Regulation of Wnt signaling during adipogenesis […]
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